VER 155008

Citations are publications that use Bio-Techne products. Selected citations for VER 155008 include:

• Amy S et al. (2021) The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer. Cancer Res. 81:1883-1895
  PMID: 33531374
• John R et al. (2021) Clathrin packets move in slow axonal transport and deliver functional payloads to synapses. Neuron. 109:2884-2901.e7
  PMID: 34534453
• Rinaldi et al. (2019) Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nat Commun. 10:2572
  PMID: 31189917
• Chiaw et al. (2019) Hsp70 and DNAJA2 limit CFTR levels through degradation. PLoS One. 14:e0220984
  PMID: 31408507
• Ganguly et al. (2017) Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 216:2059
  PMID: 28559423
• Gleixner et al. (2017) N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione. Mol Pharmacol. 92:564
  PMID: 28830914
• Jodi et al. (2016) Targeting HSP70 and GRP78 in canine osteosarcoma cells in combination with doxorubicin chemotherapy. Cell Stress Chaperones. 21:1065-1076
  PMID: 27631331
• Baquero-Perez and Whitehouse (2015) Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments. PLoS Pathog. 11:e1005274
  PMID: 26587836
• Nair et al. (2015) The regulation of TNFα production after heat and endotoxin stimulation is dependent on Annexin-A1 and HSP70. Cell Stress Chaperones. 20:583
  PMID: 25753354
• Young et al. (2015) A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90. Oncotarget. 11:113
  PMID: 25700737
• Thuringer et al. (2015) Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells. J Cell Biol. 6:10267
  PMID: 25868858
• O'Regan et al. (2015) Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression. J Biol Chem. 209:349
  PMID: 25940345
• Couceiro et al. (2015) Sequence-dependent internalization of aggregating peptides. Retrovirology. 290:242
  PMID: 25391649
• Truman et al. (2015) Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase. J Proteomics. 112:285
  PMID: 25452130
• Cavanaugh et al. (2015) Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer. Oncotarget. 6:39821
  PMID: 26556859
• Rodriguez et al. (2014) A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition. Biochim Biophys Acta. 1842:2060
  PMID: 25018089
• Traister et al. (2013) Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex. PLoS One. 8:e77331
  PMID: 24260102
• Marada et al. (2013) The unfolded protein response selectively targets active smoothened mutants. Mol Cell Biol. 33:2375
  PMID: 23572559
• Wiech et al. (2012) Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2. PLoS One. 7:e51426
  PMID: 23251530
• Shorter (2011) The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. PLoS One. 6:e26319
  PMID: 22022600
• Boroughs et al. (2011) A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration. J Biol Chem. 286:37094
  PMID: 21896482

There are no citations that match your criteria.

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• Potent HSP70 attenuation, alternative for apoptozole.

  Name: Eric Dyne
  Species: Human
  Cell Line/Tissue: Microglia
  Used this and apoptozole to knock down HSP70 expression. We ended up using Apoptozole for our work but this also worked well. Easy to reconstitute and found to be stable. Confirmed K.D. using qPCR, WB, and IF.
  Cytotoxic to microglia at higher dosages (>1uM) observed using a cell viability assay and cell imaging.
  

• VER 155008 induces PARP cleavage in U2OS cells

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Osteosarcoma
  Human osteosarcoma, U2OS, cells were incubated with VER 155008 (1 microM) for 24 h to follow PARP cleavage using Western blot. Hsp70 inhibition with VER 155008 significantly induced PARP cleavage in U2OS cells.
  

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