Valsartan

Tocris Bioscience, part of Bio-Techne | Catalog # 4216

High affinity, selective AT1 antagonist
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Key Product Details

Description

High affinity, selective AT1 antagonist

Alternative Names

CGP 48933

View all Angiotensin AT1 Receptor Antagonists »

Product Description

Valsartan is a high affinity AT1 receptor antagonist (Ki = 2.38 nM). Displays 30,000-fold selectivity over AT2 receptors. Inhibits angiotensin II-induced release of aldosterone in vitro. Orally active.

Product Specifications

Molecular Weight

435.52

Formula

C24H29N5O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid

CAS Number

137862-53-4

PubChem ID

60846

InChI Key

ACWBQPMHZXGDFX-QFIPXVFZSA-N

SMILES

CC(C)[C@@H]([C@@](O)=O)N(C(CCCC)=O)CC(C=C3)=CC=C3C1=CC=CC=C1C2=NN=NN2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 43.55 100

Preparing Stock Solutions for Valsartan

The following data is based on the product molecular weight 435.52

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.30 mL 11.48 mL 22.96 mL
5 mM 0.46 mL 2.30 mL 4.59 mL
10 mM 0.23 mL 1.15 mL 2.30 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Calculators

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Product Documents for Valsartan

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Valsartan

For research use only

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