UVI 3003

Name: UVI 3003
Brand: Tocris Bioscience
SKU: 3303

Tocris Bioscience, part of Bio-Techne | Catalog # 3303

Citations (6)

COA / SDS

New Version Available - 3912

RXR antagonist

Discontinued Product

3303 has been discontinued. An alternative/replacement product is available: 3912. View all Retinoid X Receptor Antagonists products.

Key Product Details

Description:	RXR antagonist
Chemical Name:	3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	436.58

View Full Technical Details for UVI 3003

Technical Data
Citations

Biological Activity for UVI 3003

UVI 3003 is a RXR antagonist; displays high RXR binding affinity. Does not affect the corepressor interaction capacity of the RARα subunit within the context of the RAR-RXR heterodimer.

Technical Data for UVI 3003

M. Wt	436.58
Formula	C₂₈H₃₆O₄
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	847239-17-2
PubChem ID	44566108
InChi Key	APJSHECCIRQQDV-ZRDIBKRKSA-N
Smiles	CC1(C)C2=C(C=C(C3=C(O)C=CC(/C=C/C(O)=O)=C3)C(OCCCCC)=C2)C(C)(C)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for UVI 3003

References are publications that support the biological activity of the product.

Santin Modulating retinoid X receptor with a series of (E)-3-[4-Hydroxy-3-(3-alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers. J.Med.Chem. 2009 PMID: 19408900
Nahoum Modulators of the stuctural dynamics of the retinoid X receptor to reveal receptor function. Proc.Natl.Acad.Sci.
Le Maire Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors. EMBO Rep. 2009 PMID: 19270714

UVI 3003

Tocris Bioscience, part of Bio-Techne | Catalog # 3303

Key Product Details

Biological Activity for UVI 3003

Technical Data for UVI 3003

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for UVI 3003

Product Documents for UVI 3003

COA

Certificate of Analysis

SDS

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