HX 531

Tocris Bioscience, part of Bio-Techne | Catalog # 3912

Potent RXR antagonist
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Key Product Details

Description

Potent RXR antagonist

View all Retinoid X Receptor Antagonists »

Product Description

HX 531 is a potent RXR antagonist (IC50 = 18 nM). Promotes white and brown pre-adipocyte differentiation into white adipocytes. Also inhibits bexarotene-induced brown adipogenic reprogramming of myoblasts.

Product Specifications

Molecular Weight

483.56

Formula

C29H29N3O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid

CAS Number

188844-34-0

PubChem ID

11755040

InChI Key

SXKPGYKPQPYJER-UHFFFAOYSA-N

SMILES

CC1(C)C2=C(C=C(N(C)C(C=CC([N+]([O-])=O)=C5)=C5N=C3C4=CC=C(C(O)=O)C=C4)C3=C2)C(C)(C)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.67 20

Preparing Stock Solutions for HX 531

The following data is based on the product molecular weight 483.56

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 10.34 mL 51.70 mL 103.40 mL
1 mM 2.07 mL 10.34 mL 20.68 mL
2 mM 1.03 mL 5.17 mL 10.34 mL
10 mM 0.21 mL 1.03 mL 2.07 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for HX 531

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for HX 531

For research use only

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