UK 14,304 tartrate
Tocris Bioscience, part of Bio-Techne | Catalog # 2466
α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
Key Product Details
Description
α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
Product Description
UK 14,304 tartrate is a water-soluble form of UK 14,304 (Cat. No. 0425). Full α2 adrenergic agonist. Centrally active following systemic administration in vivo.Product Specifications
Molecular Weight
442.23
Formula
C11H10BrN5.C4H6O6
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline tartrate
CAS Number
70359-46-5
PubChem ID
11236066
InChI Key
QZHBYNSSDLTCRG-UHFFFAOYSA-N
SMILES
O=C(O)C(O)C(O)C(O)=O.BrC2=C(NC3=NCCN3)C=CC1=NC=CN=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 22.11 | 50 |
Preparing Stock Solutions
for UK 14,304 tartrate
The following data is based on the product molecular weight 442.23
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.52 mL | 22.61 mL | 45.23 mL |
| 2.5 mM | 0.90 mL | 4.52 mL | 9.05 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
| 25 mM | 0.09 mL | 0.45 mL | 0.90 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chopin Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxyDA lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 1999 PMID: 9918591
- Andorn Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α2-adrenergic selectivity and different affinities for GTP. Life Sci. 1988 PMID: 2904634
- Macdonald Gene targeting - homing in on α2-adrenoceptor-subtype function. TiPS 1997 PMID: 9227000
- Cambridge UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol. 1981 PMID: 6115759
Product Specific Notices for UK 14,304 tartrate
For research use only
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