UDP disodium salt

Name: UDP disodium salt
Brand: Tocris Bioscience
SKU: 3111
Rating: 5 (1 reviews)

Tocris Bioscience a Bio-Techne Brand

Catalog # 3111

Citations (2)

(1)

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Key Product Details

Description:	Endogenous ligand; competitive antagonist at P2Y₁₄ receptors
Chemical Name:	Uridine-5'-diphosphate disodium salt
Purity:	≥97% (HPLC)
Molecular Weight:	448.12

View Full Technical Details for UDP disodium salt

Biological Activity for UDP disodium salt

UDP disodium salt is an endogenous P2Y receptor agonist which preferentially activates P2Y₆. Shown to be a competitive antagonist at P2Y₁₄ receptors.

Technical Data for UDP disodium salt

M. Wt	448.12
Formula	C₉H₁₂N₂Na₂O₁₂P₂
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	27821-45-0
PubChem ID	11957711
InChi Key	ZQKVPFKBNNAXCE-WFIJOQBCSA-L
Smiles	[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N1C=CC(=O)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for UDP disodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	44.81	100

Preparing Stock Solutions for UDP disodium salt

The following data is based on the product molecular weight 448.12.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.23 mL	11.16 mL	22.32 mL
5 mM	0.45 mL	2.23 mL	4.46 mL
10 mM	0.22 mL	1.12 mL	2.23 mL
50 mM	0.04 mL	0.22 mL	0.45 mL

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Reconstitution Calculator

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References for UDP disodium salt

References are publications that support the biological activity of the product.

Fricks UDP is a competitive antagonist at the human P2Y₁₄ receptor. J.Pharmacol.Exp.Ther. 2008 PMID: 18252808
Ralevic and Burnstock Receptors for purines and pyrimidines. Pharmacol.Rev. 1998 PMID: 9755289

Citations for UDP disodium salt (2)

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Citations are publications that use Bio-Techne products. Selected citations for UDP disodium salt include:

Obba et al. (2015) The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Alcohol Clin Exp Res. 11:1114
PMID: 26029847
Ilatovskaya et al. (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol. 305:C1050
PMID: 24048730

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Customer Reviews for UDP disodium salt (1)

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P2Y6 activation (P2Y6)

Name: Anonymous

Species: Mouse

Assay Type: Ex Vivo

Applied directly on a tissue slice to activate P2Y receptors (P2Y6 mostly). Elicited expected cellular response.

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Product Documents for UDP disodium salt

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.