TM 5275 sodium salt

Name: TM 5275 sodium salt
Brand: Tocris Bioscience
SKU: 5769

Tocris Bioscience, part of Bio-Techne | Catalog # 5769

Citations (1)

COA / SDS

Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable

Key Product Details

Description:	Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable
Chemical Name:	5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	543.97

View Full Technical Details for TM 5275 sodium salt

Technical Data
Citations

Biological Activity for TM 5275 sodium salt

TM 5275 sodium salt is a plasminogen activator inhibitor-1 (PAI-1) inhibitor. Orally bioavailable.

Compound Libraries for TM 5275 sodium salt

TM 5275 sodium salt is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for TM 5275 sodium salt

M. Wt	543.97
Formula	C₂₈H₂₇ClN₃NaO₅
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	1103926-82-4
PubChem ID	53240409
InChi Key	JSHSGBIWNPQCQZ-UHFFFAOYSA-M
Smiles	O=C(COCC(NC4=C(C(O[Na])=O)C=C(Cl)C=C4)=O)N1CCN(C(C3=CC=CC=C3)C2=CC=CC=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TM 5275 sodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	54.4	100

Preparing Stock Solutions for TM 5275 sodium salt

The following data is based on the product molecular weight 543.97.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.84 mL	9.19 mL	18.38 mL
5 mM	0.37 mL	1.84 mL	3.68 mL
10 mM	0.18 mL	0.92 mL	1.84 mL
50 mM	0.04 mL	0.18 mL	0.37 mL

Molarity Calculator

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Reconstitution Calculator

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References for TM 5275 sodium salt

References are publications that support the biological activity of the product.

Yamaoka Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors. Chem.Pharm.Bull. 2011 PMID: 21297302