Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Potent and selective MC4 receptor agonist|
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Citations for THIQ (3)
Citations are publications that use Bio-Techne products. Selected citations for THIQ include:
Garfield et al.
A neural basis for melanocortin-4 receptor-regulated appetite.
Huang and Tao
A small molecule agonist THIQ as a novel pharmacoperone for intracellularly retained melanocortin-4 receptor mutants.
Sohn et al.
Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons.
Int J Biol Sci.
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Customer Reviews for THIQ (1)
Species: MouseAssay Type: In VivoRecently, we demonstrated that the deletion of the NFKB1 gene, which encodes the p50 NF-kappa B subunit, causes impairment in social behaviours, with reductions in social interactions in mice. In this work, we tested the acute effects of THIQ, a selective melanocortin 4 receptor (MC4R) agonist. THIQ treatment increased social interactions both in wild type and p50-/- mice. In particular, after treatment with THIQ, p50-/- mice showed a prosocial behaviour analogous to that of basal WT mice.
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