Thalidomide 4'-oxyacetamide-PEG3-amine

Tocris Bioscience, part of Bio-Techne | Catalog # 6467

Cereblon ligand with PEG linker and terminal amine for onward chemistry
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Key Product Details

Description

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternative Names

Thalidomide - linker 1

View all Cereblon Ligands plus Linker Building Blocks »

Product Description

Thalidomide 4'-oxyacetamide-PEG3-amine is a functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 1

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

542.97

Formula

C23H30N4O9.HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride

CAS Number

2245697-84-9

PubChem ID

134160246

InChI Key

ORRMBTUTYKQYQU-UHFFFAOYSA-N

SMILES

O=C(C1=C(C(OCC(NCCOCCOCCOCCN)=O)=CC=C1)C2=O)N2C(C(N3)=O)CCC3=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Thalidomide 4'-oxyacetamide-PEG3-amine

Certificate of Analysis

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Product Specific Notices for Thalidomide 4'-oxyacetamide-PEG3-amine

For research use only

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