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Tetrabenazine

Tocris Bioscience a Bio-Techne Brand

Vesicular Monoamine Transporter Inhibitors Small Molecule
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2175/10
2175/50
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Key Product Details

Description: Potent inhibitor of vesicular monoamine transport
Chemical Name: (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
Purity: ≥98% (HPLC)
Molecular Weight: 317.2

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  • Depletion of dopamine stores
    Name: Sergiy Sylantyev
    Species: Human
    Cell Line/Tissue: Stem cell - derived neurons
    Tetrabenazine (TBZ) was used to deplete dopamine stores in cultured dopamine neurons and thus counteract dopamine-generated allosteric antagonism at NMDA receptors. 20-minute incubation of cell culture in 1 µM tetrabenazine had led to significant amplitude increase of NMDA-receptor – generated series of evoked post-synaptic potentials (see illustration).
    Tetrabenazine Serum 2175

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Product Documents for Tetrabenazine

Certificate of Analysis

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