Selective blocker of inward-rectifier K+ channels
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Key Product Details
Description: | Selective blocker of inward-rectifier K+ channels |
Purity: | ≥95% (HPLC) |
Molecular Weight: | 2452 |
Citations for Tertiapin-Q (10)
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Citations are publications that use Bio-Techne products. Selected citations for Tertiapin-Q include:
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Patel et al.
(2020)
Structural Determinants Mediating Tertiapin Block of Neuronal Kir3.2 Channels.
Biochemistry.
59:836
PMID: 31990535 -
Aguilar-Sanchez et al.
(2019)
Transmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level.
Front Physiol.
10:773
PMID: 31333477 -
Llamosas et al.
(2017)
Inactivation of GIRK channels weakens the pre- and postsynaptic inhibitory activity in dorsal raphe neurons.
Physiol Rep.
5
PMID: 28196855 -
Workman et al.
(2015)
Rapid antidepressants stimulate the decoupling of GABAB receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η.
Mol Psychiatry.
20:298
PMID: 25560757 -
Stott et al.
(2015)
Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats.
Hypertension.
65:676
PMID: 25547342 -
Marcott et al.
(2014)
Phasic DA release drives rapid activation of striatal D2-receptors.
Neuron.
84:164
PMID: 25242218 -
Chu et al.
(2013)
Effects of stresscopin on rat hypothalamic paraventricular nucleus neurons in vitro.
PLoS One.
8:e53863
PMID: 23349753 -
Choisy et al.
(2012)
Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart.
PLoS One.
7:e33448
PMID: 22479400 -
Choisy et al.
(2012)
Acute desensitization of acetylcholine and endothelin-1 activated inward rectifier K+ current in myocytes from the cardiac atrioventricular node.
Biochem Biophys Res Commun.
423:496
PMID: 22683635 -
Yi et al.
(2011)
Sperm GIRK2-containing K+ inward rectifying channels participate in sperm capacitation and fertilization.
Syst Biol Reprod Med.
57:296
PMID: 22054410
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Customer Reviews for Tertiapin-Q (2)
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Species: MouseCell Line/Tissue: Bed nucleus of the stria terminalisWe performed ex-vivo slice physiology and pre-incubated the slices in tertiapin-Q (200 nM). Pre-incubation blocked inward rectifying channels.
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Species: HumanAssay Type: In VitroThe product shows great Kir channel blocking properties even at very small cocentrations, the data was reproducible every time.
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