TCS 2002
Tocris Bioscience, part of Bio-Techne | Catalog # 3869
Potent GSK-3β inhibitor
Product Description
TCS 2002 is a potent inhibitor of GSK-3β (IC50 = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain.Product Specifications
Molecular Weight
338.38
Formula
C18H14N2O3S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-Methyl-5-[3-[4-(methylsulfinyl)phenyl]-5-benzofuranyl]-1,3,4-oxadiazole
CAS Number
1005201-24-0
PubChem ID
24855958
InChI Key
RCKYSTKYIVULEK-UHFFFAOYSA-N
SMILES
O=S(C)C(C=C3)=CC=C3C2=COC1=CC=C(C4=NN=C(C)O4)C=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.84 | 100 | |
| Ethanol | 8.46 | 25 |
Preparing Stock Solutions
for TCS 2002
The following data is based on the product molecular weight 338.38
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.96 mL | 14.78 mL | 29.55 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.91 mL |
| 10 mM | 0.30 mL | 1.48 mL | 2.96 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.59 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for TCS 2002
For research use only
Loading...
Loading...