TC SL C5

Tocris Bioscience, part of Bio-Techne | Catalog # 6884

Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
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Key Product Details

Description

Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor

Alternative Names

SM5,MALAT1-IN-1

View all DNA Methyltransferase Inhibitors »

Product Description

TC SL C5 is a metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor (KD = 2.9 μM). Binds Malat1 3' terminal stability element for nuclear expression (ENE) triplex. Reduces Malat1 RNA levels by 54% and branching morphogenesis by 38% in mammary tumor organoids. Modulates Malat1 downstream genes without affecting Neat1.

Product Specifications

Molecular Weight

323.40

Formula

C19H21N3O2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

5-(4-Methoxyphenyl)-N-[(3-methoxyphenyl)methyl]-1-methyl-1H-Imidazol-2-amine

CAS Number

827327-28-6

PubChem ID

1096509

InChI Key

LCVOJBGSGIOMKF-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1)C1=CN=C(NCC2=CC(OC)=CC=C2)N1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.34 100
Ethanol 32.34 100

Preparing Stock Solutions for TC SL C5

The following data is based on the product molecular weight 323.40

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.09 mL 15.46 mL 30.92 mL
5 mM 0.62 mL 3.09 mL 6.18 mL
10 mM 0.31 mL 1.55 mL 3.09 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for TC SL C5

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TC SL C5

For research use only

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