TC LPA5 4

Tocris Bioscience, part of Bio-Techne | Catalog # 4708

LPA5 receptor antagonist
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Key Product Details

Description

LPA5 receptor antagonist

View all Lysophosphatidic Acid (LPA) Receptor Antagonists »

Product Description

TC LPA5 4 is an LPA5 receptor antagonist (IC50 = 0.8 μM in LPA5-RH7777 cells). TC LPA5 4 inhibits LPA-induced aggregation of isolated human platelets. Exhibits selectivity for LPA5 against 80 other screened targets.

Product Specifications

Molecular Weight

410.89

Formula

C23H23ClN2O3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

5-(3-Chloro-4-cyclohexylphenyl)-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylic acid

CAS Number

1393814-38-4

PubChem ID

66552906

InChI Key

BNALUYKEGYUHQC-UHFFFAOYSA-N

SMILES

ClC(C=C(C3=CC(C(O)=O)=NN3C4=CC=CC(OC)=C4)C=C2)=C2C1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.09 100
Ethanol 8.22 20

Preparing Stock Solutions for TC LPA5 4

The following data is based on the product molecular weight 410.89

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.43 mL 12.17 mL 24.34 mL
5 mM 0.49 mL 2.43 mL 4.87 mL
10 mM 0.24 mL 1.22 mL 2.43 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for TC LPA5 4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TC LPA5 4

For research use only

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