TC AQP1 1
Tocris Bioscience, part of Bio-Techne | Catalog # 5412
Aquaporin 1 (AQP1) channel blocker
Key Product Details
Description
Aquaporin 1 (AQP1) channel blocker
Product Description
TC AQP1 1 is an aquaporin 1 (AQP1) channel blocker (IC50 = 8 μM). Inhibits water flux in Xenopus oocytes.Product Specifications
Molecular Weight
218.211
Formula
C12H10O4
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
3,3'-(1,3-Phenylene)bis(2-propenoic acid)
CAS Number
37710-81-9
PubChem ID
794091
InChI Key
KRXUBZPHAPGHPE-YDFGWWAZSA-N
SMILES
O=C(O)/C=C/C1=CC(/C=C/C(O)=O)=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.82 | 100 |
Preparing Stock Solutions
for TC AQP1 1
The following data is based on the product molecular weight 218.211
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.58 mL | 22.91 mL | 45.83 mL |
| 5 mM | 0.92 mL | 4.58 mL | 9.17 mL |
| 10 mM | 0.46 mL | 2.29 mL | 4.58 mL |
| 50 mM | 0.09 mL | 0.46 mL | 0.92 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Seeliger Discovery of novel human aquaporin-1 blockers. ACS Chem.Biol. 2013 PMID: 23113556
Product Specific Notices for TC AQP1 1
For research use only
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