TAPI 2

Tocris Bioscience, part of Bio-Techne | Catalog # 6013

ADAM-17 (TACE) and MMP inhibitor
Catalog #
Availability
Size / Price
Qty
6013/1
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

ADAM-17 (TACE) and MMP inhibitor

View all Matrix Metalloprotease (MMP) Inhibitors »

Product Description

TAPI 2 is an ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.

This product is typically reconstituted in water.

Product Specifications

Molecular Weight

415.54

Formula

C19H37N5O5

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide

CAS Number

689284-12-6

PubChem ID

10093303

InChI Key

LMIQCBIEAHJAMZ-RMTCENKZSA-N

SMILES

ONC(C[C@@H](CC(C)C)C(N[C@@H](C(C)(C)C)C(N[C@@H](C)C(NCCN)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for TAPI 2

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TAPI 2

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.