TAPI 1

Tocris Bioscience, part of Bio-Techne | Catalog # 6162

ADAM-17 (TACE) and MMP inhibitor
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Key Product Details

Description

ADAM-17 (TACE) and MMP inhibitor

View all Matrix Metalloprotease (MMP) Inhibitors »

Product Description

TAPI 1 is a TACE/ADAM-17 and MMP inhibitor. Blocks shedding of TNF from cell membranes. Reduces pain-associated behavior in mice with a constructive mononeuropathy.

This product is typically reconstituted in DMSO.

Product Specifications

Molecular Weight

499.60

Formula

C26H37N5O5

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide

CAS Number

163847-77-6

PubChem ID

9827273

InChI Key

AWNBSWDIOCXWJW-OWHMDLSXSA-N

SMILES

ONC(C[C@@H](CC(C)C)C(N[C@@H](CC1=CC(C=CC=C2)=C2C=C1)C(N[C@@H](C)C(NCCN)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for TAPI 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TAPI 1

For research use only

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