SUN-B 8155

Name: SUN-B 8155
Brand: Tocris Bioscience
SKU: 2550
Price: 209 USD

Tocris Bioscience a Bio-Techne Brand

Catalog # 2550

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Key Product Details

Description:	Non-peptide calcitonin agonist
Chemical Name:	5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone
Molecular Weight:	273.29

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Biological Activity for SUN-B 8155

SUN-B 8155 is a non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC₅₀ = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.

Compound Libraries for SUN-B 8155

SUN-B 8155 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for SUN-B 8155

M. Wt	273.29
Formula	C₁₄H₁₅N₃O₃
Storage	Store at +4°C
CAS Number	345893-91-6
PubChem ID	16079007
InChi Key	IMUCOECFKIWBSW-LCYFTJDESA-N
Smiles	O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SUN-B 8155

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	27.32	100

Preparing Stock Solutions for SUN-B 8155

The following data is based on the product molecular weight 273.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.66 mL	18.30 mL	36.59 mL
5 mM	0.73 mL	3.66 mL	7.32 mL
10 mM	0.37 mL	1.83 mL	3.66 mL
50 mM	0.07 mL	0.37 mL	0.73 mL

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References for SUN-B 8155

References are publications that support the biological activity of the product.

Katayama Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin. Biochim.Biophys.Acta 2001 PMID: 11325540

Citations for SUN-B 8155

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SUN-B 8155

Tocris Bioscience a Bio-Techne Brand

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