st-Ht31

Name: st-Ht31
Brand: Tocris Bioscience
SKU: 6286

Tocris Bioscience, part of Bio-Techne | Catalog # 6286

Citations (8)

COA / SDS

Inhibits PKA/AKAP interactions; cell permeable

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Technical Data
Citations & Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Inhibits PKA/AKAP interactions; cell permeable

View all Protein Kinase A Compounds »

Product Description

st-Ht31 is a stearated form of the peptide Ht-31. Inhibits the interaction between the RII subunits of cAMP-dependent PKA and A-kinase anchoring protein (AKAP) in cell extracts. Cell permeable.

Product Specifications

Molecular Weight

2798.27

Formula

C₁₂₉H₂₁₇N₂₉O₃₉

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

188425-80-1

PubChem ID

16143012

InChI Key

AHVAWKAVLPRRQS-MUBBMYIHSA-N

SMILES

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in 0.01M PBS (pH 7.4)

Calculators

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Background References

References are publications that support the biological activity of the product.

Stival Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm. J.Biol.Chem. 2018 PMID: 29700114
Vijayaraghavan Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J.Biol.Chem. 1997 PMID: 9030527
Carr Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. J.Biol.Chem. 1992 PMID: 1618839
Gorshkov AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat.Chem.Biol. 2017 PMID: 28192412