SRT 1720

Tocris Bioscience, part of Bio-Techne | Catalog # 7558

Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
Catalog #
Availability
Size / Price
Qty
7558/10
7558/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis

View all Sirtuin 1/SIRT1 Activators »

Product Description

SRT 1720 is selective SIRT 1 activator (EC50 = 0.16 μM). SRT 1720 inhibits growth of bladder cancer organoids and xenografts (IC50 = 0.35 μM) and induces autophagy. In vitro, SRT 1720 increases mitochondrial biogenesis and recovery after oxidation injury and reduces palmitate-induced insulin resistance. Also improves survival and healthspan of obese mice.

Product Specifications

Molecular Weight

469.56

Formula

C25H23N7OS

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide

CAS Number

925434-55-5

PubChem ID

24180125

InChI Key

IASPBORHOMBZMY-UHFFFAOYSA-N

SMILES

O=C(NC=1C=CC=CC1C=2N=C3SC=C(N3C2)CN4CCNCC4)C5=NC6=CC=CC=C6N=C5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.35 5

Preparing Stock Solutions for SRT 1720

The following data is based on the product molecular weight 469.56

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 42.59 mL 212.97 mL 425.93 mL
0.25 mM 8.52 mL 42.59 mL 85.19 mL
0.5 mM 4.26 mL 21.30 mL 42.59 mL
2.5 mM 0.85 mL 4.26 mL 8.52 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for SRT 1720

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SRT 1720

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.