SR 11302

Tocris Bioscience, part of Bio-Techne | Catalog # 2476

AP-1 inhibitor; antitumor agent
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Key Product Details

Description

AP-1 inhibitor; antitumor agent

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Product Description

SR 11302 is an inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo. Does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50 > 1 μM for RARα, RARβ, RARγ and RXRα).

Product Specifications

Molecular Weight

376.54

Formula

C26H32O2

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid

CAS Number

160162-42-5

PubChem ID

9976842

InChI Key

RQANARBNMTXCDM-DKOHIBGUSA-N

SMILES

CC(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)C1=CC=C(C)C=C1)=C/C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.6 100
Ethanol 3.76 10

Preparing Stock Solutions for SR 11302

The following data is based on the product molecular weight 376.54

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.66 mL 13.28 mL 26.56 mL
5 mM 0.53 mL 2.66 mL 5.31 mL
10 mM 0.27 mL 1.33 mL 2.66 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SR 11302

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SR 11302

For research use only

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