SNC 80

Tocris Bioscience, part of Bio-Techne | Catalog # 0764

Citations (123)

COA / SDS

Highly selective non-peptide δ agonist

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Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Highly selective non-peptide δ agonist

View all delta Opioid Receptor Agonists »

Product Description

SNC 80 is a highly selective and potent non-peptide δ-opioid agonist, 2000-fold selective over μ-opioid receptors.

Product Specifications

Molecular Weight

449.64

Formula

C₂₈H₃₉N₃O₂

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide

CAS Number

156727-74-1

PubChem ID

123924

InChI Key

KQWVAUSXZDRQPZ-UMTXDNHDSA-N

SMILES

[H][C@@](N1C[C@@H](C)N(CC=C)C[C@@H]1C)(C1=CC=C(C=C1)C(=O)N(CC)CC)C1=CC=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	1eq. HCl	44.96	100 with gentle warming
	DMSO	8.99	20

Preparing Stock Solutions for SNC 80

The following data is based on the product molecular weight 449.64

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.22 mL	11.12 mL	22.24 mL
5 mM	0.44 mL	2.22 mL	4.45 mL
10 mM	0.22 mL	1.11 mL	2.22 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Calderon Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC80): a highly selective nonpeptid J.Med.Chem. 1994 PMID: 8035418
Knapp Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. J.Pharmacol.Exp.Ther. 1996 PMID: 8667189
Bilsky SNC 80, a selective, nonpeptidic and systemically active opioid δ agonist. J.Pharmacol.Exp.Ther. 1995 PMID: 7714789