SNAP

Name: SNAP
Brand: Tocris Bioscience
SKU: 0598
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0598

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Citations (60)

COA / SDS

A stable analog of endogenous S-nitroso compounds

Key Product Details

Description:	A stable analog of endogenous S-nitroso compounds
Chemical Name:	(S)-Nitroso-N-acetylpenicillamine
Molecular Weight:	220.24

View Full Technical Details for SNAP

Technical Data
Citations / Reviews (1)

Biological Activity for SNAP

SNAP is a stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t_½ of 37h.

Technical Data for SNAP

M. Wt	220.24
Formula	C₇H₁₂N₂O₄S
Storage	Store at -20°C
CAS Number	79032-48-7
PubChem ID	5231
InChi Key	ZIIQCSMRQKCOCT-UHFFFAOYSA-N
Smiles	O=NSC(C)(C)C(NC(C)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SNAP

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	22.02	100

Preparing Stock Solutions for SNAP

The following data is based on the product molecular weight 220.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.54 mL	22.70 mL	45.41 mL
5 mM	0.91 mL	4.54 mL	9.08 mL
10 mM	0.45 mL	2.27 mL	4.54 mL
50 mM	0.09 mL	0.45 mL	0.91 mL

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Reconstitution Calculator

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References for SNAP

References are publications that support the biological activity of the product.

Ferrero Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: correlation with nitric oxide production. Br.J.Pharmacol. 1999 PMID: 10401570
Cross Neurotoxicity in conscious rats following intraventricular SNAP, a nitric oxide donor. Neuropharmacology 1994 PMID: 7969812
Ekblad and Sundler Motor responses in rat ileum evoked by nitric oxide donors vs. field stimulation: modulation by pituitary adenylate cyclase-activating peptide, forskolin and guanylate cyclase inhibitors. J.Pharmacol.Exp.Ther. 1997 PMID: 9336304
Bauer and Fung Differential thermodynamic effects and tolerance properties of nitrogly. and S-nitrosothiol in experimental heart failure. J.Pharmacol.Exp.Ther. 1991 PMID: 1899118