SNAP 94847 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3347

Potent and selective MCH1 antagonist
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Key Product Details

Description

Potent and selective MCH1 antagonist

View all Melanin-concentrating Hormone Receptor Antagonists »

Product Description

SNAP 94847 hydrochloride is a potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding in vivo. Exhibits anxiolytic activity and is orally active.

Product Specifications

Molecular Weight

515.03

Formula

C29H32F2N2O2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride

CAS Number

1781934-47-1

PubChem ID

56972235

InChI Key

DEDUDFNRQKUBRH-UHFFFAOYSA-N

SMILES

CC1=CC=C(NC(C(C)C)=O)C=C1C(CC4)CCN4CC(C=C3)=CC=C3OC2=CC(F)=C(F)C=C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 51.5 100
Ethanol 51.5 100

Preparing Stock Solutions for SNAP 94847 hydrochloride

The following data is based on the product molecular weight 515.03

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.94 mL 9.71 mL 19.42 mL
5 mM 0.39 mL 1.94 mL 3.88 mL
10 mM 0.19 mL 0.97 mL 1.94 mL
50 mM 0.04 mL 0.19 mL 0.39 mL

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Product Documents for SNAP 94847 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SNAP 94847 hydrochloride

For research use only

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