SLU-PP-332
Tocris Bioscience, part of Bio-Techne | Catalog # 8112
Potent pan-ERR agonist
Key Product Details
Description
Potent pan-ERR agonist
Product Description
SLU-PP-332 is a potent and selective pan estrogen related receptor (ERR) agonist (EC50 values are 98 nM, 230 nM and 430 nM for ERRα, ERRβ and ERRγ respectively). In a mouse model of metabolic syndrome SLU-PP-332 increases energy expenditure and fatty acid oxidation, decreases fat mass, and improves insulin sensitivity. Also increases mitochondrial respiration in vitro.Product Specifications
Molecular Weight
290.32
Formula
C18H14N2O2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide
CAS Number
303760-60-3
PubChem ID
5404083
InChI Key
RNZIMBFHRXYRLL-XDHOZWIPSA-N
SMILES
O=C(C1=CC=C(C=C1)O)N/N=C/C2=CC3=C(C=CC=C3)C=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.03 | 100 |
Preparing Stock Solutions
for SLU-PP-332
The following data is based on the product molecular weight 290.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.44 mL | 17.22 mL | 34.44 mL |
| 5 mM | 0.69 mL | 3.44 mL | 6.89 mL |
| 10 mM | 0.34 mL | 1.72 mL | 3.44 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.69 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Billon A synthetic ERR agonist alleviates metabolic syndrome. J.Pharmacol.Exp.Ther. 2024 PMID: 37739806
- Billon Synthetic ERRα/β/γ agonist induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chem.Biol. 2023 PMID: 36988910
Product Specific Notices for SLU-PP-332
For research use only
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