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SKF 96365 hydrochloride

Tocris Bioscience a Bio-Techne Brand

TRPC Channel Blockers Small Molecule
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1147/50
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Key Product Details

Description: TRPC channel inhibitor; also inhibits store-operated Ca2+ entry
Chemical Name: 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydrochloride
Purity: ≥99% (HPLC)
Molecular Weight: 402.92

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Citations for SKF 96365 hydrochloride (14)

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Customer Reviews for SKF 96365 hydrochloride (3)

4.7 out of 5
3 customer ratings
5 stars
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4 stars
33%
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  • It can inhibit TRPC1 channel
    Name: Yuyang Sun
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HSG
    Used SKF to test TRPC1 channel; it can inhibit the Tg induced SOCE entry.
    SKF 96365 hydrochloride Serum 1147
  • Tested for store operated calcium entry inhibiting activity
    Name: ANANTH KUMAR KAMMALA
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Mast cells LAD2
    SKF96365 HCL was used to study the Invitro Calcium mobilization assay, cytokine assay in human mast cells (LAD2), and Invivo mast cell-dependent inflammation studies. SKF96365 at a concentration of 30,50 and 100uM has inhibited the calcium mobilization via the MRGPRX2 pathway and reduced the inflammation in mast cell dependent invivo paw edema and rosacea experiments. SKF965365 HCL is the best compound to study the store-operated calcium entry assays.
    SKF 96365 hydrochloride Serum 1147
  • a Store-operated channel blocker
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: microglia
    SKF96365 at 20 microM blocks intracellular calcium influx through a store-operated channel in microglia culture.

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Product Documents for SKF 96365 hydrochloride

Certificate of Analysis

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