SGC AAK1 1N
Tocris Bioscience, part of Bio-Techne | Catalog # 6529
Negative control for SGC AAK1 1 (Cat.No. 6528)
Key Product Details
Description
Negative control for SGC AAK1 1 (Cat.No. 6528)
Product Description
SGC AAK1 1N is a negative control for SGC AAK1 1 (Cat. No. 6528).Licensing Information
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC-AAK1-1 probe summary on the SGC website.Product Specifications
Molecular Weight
398.48
Formula
C20H22N4O3S
Storage
Store at -20°C
Purity
≥97% (HPLC)
Chemical Name
N-[6-[3-[(Cyclopropylsulfonyl)amino]phenyl]-1H-indazol-3-yl]-2-methylpropanamide
CAS Number
2242913-80-8
PubChem ID
146121078
InChI Key
RAIAORGFMNXPOV-UHFFFAOYSA-N
SMILES
O=C(C(C)C)NC1=NNC2=C1C=CC(C3=CC=CC(NS(=O)(C4CC4)=O)=C3)=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.85 | 100 | |
| Ethanol | 3.98 | 10 |
Preparing Stock Solutions
for SGC AAK1 1N
The following data is based on the product molecular weight 398.48
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.51 mL | 12.55 mL | 25.10 mL |
| 5 mM | 0.50 mL | 2.51 mL | 5.02 mL |
| 10 mM | 0.25 mL | 1.25 mL | 2.51 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.50 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Agajanian WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop. Cell Rep. 2019 PMID: 30605688
Product Specific Notices for SGC AAK1 1N
For research use only
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