SEW 2871

Tocris Bioscience, part of Bio-Techne | Catalog # 2284

Cell-permeable, selective S1P1 receptor agonist
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Key Product Details

Description

Cell-permeable, selective S1P1 receptor agonist

View all Sphingosine-1-phosphate Receptor Agonists »

Product Description

SEW 2871 is a novel, potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo.

Product Specifications

Molecular Weight

440.36

Formula

C20H10F6N2OS

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]1,2,4-oxadiazole

CAS Number

256414-75-2

PubChem ID

4077460

InChI Key

OYMNPJXKQVTQTR-UHFFFAOYSA-N

SMILES

FC(F)(F)C1=C(C=C(S1)C1=NC(=NO1)C1=CC(=CC=C1)C(F)(F)F)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 8.81 20
Ethanol 8.81 20

Preparing Stock Solutions for SEW 2871

The following data is based on the product molecular weight 440.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 11.35 mL 56.77 mL 113.54 mL
1 mM 2.27 mL 11.35 mL 22.71 mL
2 mM 1.14 mL 5.68 mL 11.35 mL
10 mM 0.23 mL 1.14 mL 2.27 mL

Calculators

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Reconstitution Calculator

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Product Documents for SEW 2871

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SEW 2871

For research use only

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