Senktide
Tocris Bioscience, part of Bio-Techne | Catalog # 1068
Tachykinin NK3 agonist
Product Description
Senktide is a NK3 tachykinin receptor agonist. Causes direct excitation of dopamine neurons; enhances dopaminergic function. Induces locomotor activity.Product Specifications
Molecular Weight
841.97
Formula
C40H55N7O11S
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
106128-89-6
PubChem ID
90479751
InChI Key
UGXWLDUHYDFTIA-QKUYTOGTSA-N
SMILES
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC1=CC=C(C)C=C1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(O)=O)NC(=O)CCC(O)=O)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in PBS (pH 7.4) |
Calculators
Molarity Calculator
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Background References
References are publications that support the biological activity of the product.
- Nordquist The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils. Eur.J.Pharmacol. 2008 PMID: 18930726
- Renzetti Characterization of NK-3 binding sites in rat and guinea-pig cortical membranes by the selective ligand [3H]senktide. Neuropeptides 1991 PMID: 1712430
- Keegan The selective NK receptor agonist senktide excites a subpopulation of DA-sensitive neurones in the rat substantia nigra pars compacta in vitro. Br.J.Pharmacol. 1992 PMID: 1375857
Product Specific Notices for Senktide
For research use only
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