SB 399885 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3189

Potent and selective 5-HT6 antagonist
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Key Product Details

Description

Potent and selective 5-HT6 antagonist

View all 5-HT6 Receptor Antagonists »

Product Description

SB 399885 hydrochloride is a potent, brain penetrant, orally active 5-HT6 antagonist. Displays > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors respectively).

Product Specifications

Molecular Weight

482.81

Formula

C18H21Cl2N3O4S.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride

CAS Number

402713-81-9

PubChem ID

6918649

InChI Key

ATKZKAYWARYLBW-UHFFFAOYSA-N

SMILES

Cl.ClC1=CC(Cl)=CC(NS(C2=CC(N3CCNCC3)=C(OC)C=C2)(=O)=O)=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 48.28 100
DMSO 48.28 100

Preparing Stock Solutions for SB 399885 hydrochloride

The following data is based on the product molecular weight 482.81

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.07 mL 10.36 mL 20.71 mL
5 mM 0.41 mL 2.07 mL 4.14 mL
10 mM 0.21 mL 1.04 mL 2.07 mL
50 mM 0.04 mL 0.21 mL 0.41 mL

Calculators

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Reconstitution Calculator

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Product Documents for SB 399885 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SB 399885 hydrochloride

For research use only

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