SB 222200

Tocris Bioscience, part of Bio-Techne | Catalog # 1393

Potent, selective non-peptide NK3 antagonist. Brain penetrant
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Key Product Details

Description

Potent, selective non-peptide NK3 antagonist. Brain penetrant

View all NK3 Receptor Antagonists »

Product Description

SB 222200 is a potent and selective non-peptide NK3 receptor antagonist (Ki values are 4.4, > 100,000 and 250 nM for human NK3, NK1 and NK2 receptors respectively). Antihypertensive in vivo. Brain penetrant.

Licensing Information

Sold under license

Product Specifications

Molecular Weight

380.48

Formula

C26H24N2O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide

CAS Number

174635-69-9

PubChem ID

6604009

InChI Key

MQNYRKWJSMQECI-QFIPXVFZSA-N

SMILES

O=C(C2=C(C)C(C4=CC=CC=C4)=NC3=CC=CC=C23)N[C@@H](CC)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100
Ethanol 100

Preparing Stock Solutions for SB 222200

The following data is based on the product molecular weight 380.48

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL
10 mM 0.26 mL 1.31 mL 2.63 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

Calculators

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Reconstitution Calculator

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Product Documents for SB 222200

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SB 222200

For research use only

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