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(S)-SNAP 5114

Catalog # 1561 | Tocris Bioscience a Bio-Techne Brand
GABA uptake inhibitor
GABA uptake inhibitor
Introduction to Tocris

Key Product Details

Description: GABA uptake inhibitor
Chemical Name: 1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid
Purity: ≥98% (HPLC)
Molecular Weight: 505.61

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  • Modulation of action potentials
    Name: Sergiy Sylantyev
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Hippocampus
    (S)-SNAP 5114 was used to block a GAT-3 GABA transporter in hippocampal neural tissue. Application of (S)-SNAP 5114 decreased significantly the spiking probability in hippocampal neurons and coincidence detection time window for excitatory inputs (see illustration). 20 min. washout restored the spiking probability to ~70-80% of control value.
    Preparation of 10 mM stock requires sonication.
    (S)-SNAP 5114 Serum 1561

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Product Documents for (S)-SNAP 5114

Certificate of Analysis

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