(S)-(-)-Carbidopa
Tocris Bioscience, part of Bio-Techne | Catalog # 0455
Aromatic L-amino acid decarboxylase inhibitor
Key Product Details
Description
Aromatic L-amino acid decarboxylase inhibitor
Product Description
(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.Product Specifications
Molecular Weight
226.23
Formula
C10H14N2O4
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
CAS Number
28860-95-9
PubChem ID
34359
InChI Key
TZFNLOMSOLWIDK-JTQLQIEISA-N
SMILES
OC1=C(O)C=CC(C[C@@](NN)(C)C(O)=O)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.52 | 20 |
Preparing Stock Solutions
for (S)-(-)-Carbidopa
The following data is based on the product molecular weight 226.23
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 22.10 mL | 110.51 mL | 221.01 mL |
| 1 mM | 4.42 mL | 22.10 mL | 44.20 mL |
| 2 mM | 2.21 mL | 11.05 mL | 22.10 mL |
| 10 mM | 0.44 mL | 2.21 mL | 4.42 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kopfhammer L-Dopa infusion experiments in combination with the L-dopa decarboxylase inhibitors benserazide and carb. - L-dopa metabolism and neuroendocrinological effects. Pharmacopsychiatry
- Cheng Carbidopa inhibition of aromatic L-amino acid decarboxylase in rat brain capilliaries. FASEB J.
Product Specific Notices for (S)-(-)-Carbidopa
For research use only
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