(S)-(+)-α-Methylhistamine dihydrobromide

Name: ( S )-(+)- α -Methylhistamine dihydrobromide
Brand: tocris
SKU: 0572

Catalog # 0572

Datasheet / COA / SDS

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Key Product Details

Description:	H₃ agonist, less active enantiomer
Chemical Name:	(S)-(+)-α-Methyl-1H-imidazole-4-ethanamine dihydrobromide

View Full Technical Details for (S)-(+)-α-Methylhistamine dihydrobromide

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Biological Activity

Less active enantiomer of H₃ agonist R-(-)-α-methylhistamine; 120-fold less potent than R-(-) at H₃.

R-enantiomer also available.

Technical Data

M. Wt	287
Formula	C₆H₁₁N₃.2HBr
Storage	Desiccate at RT
PubChem ID	45073439
InChi Key	RWHNAAABSGVRDT-XRIGFGBMSA-N
Smiles	N[C@@H](C)CC1=CNC=N1.Br.Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 287.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.48 mL	17.42 mL	34.84 mL
5 mM	0.70 mL	3.48 mL	6.97 mL
10 mM	0.35 mL	1.74 mL	3.48 mL
50 mM	0.07 mL	0.35 mL	0.70 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Hill Distribution, properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 1990 PMID: 2164693