(S)-4-Carboxy-3-hydroxyphenylglycine

Name: ( S )-4-Carboxy-3-hydroxyphenylglycine
Brand: Tocris Bioscience
SKU: 0320

Tocris Bioscience, part of Bio-Techne | Catalog # 0320

Citations (1)

COA / SDS

Group I mGlu antagonist; also group II mGlu agonist

Discontinued Product

0320 has been discontinued. View all Group I mGluR Antagonists products.

Key Product Details

Description:	Group I mGlu antagonist; also group II mGlu agonist
Alternative Names:	(S)-4C3HPG
Purity:	≥98% (HPLC)
Molecular Weight:	211.17

View Full Technical Details for (S)-4-Carboxy-3-hydroxyphenylglycine

Technical Data
Citations

Biological Activity for (S)-4-Carboxy-3-hydroxyphenylglycine

(S)-4-Carboxy-3-hydroxyphenylglycine is a competitive antagonist at group I mGlu_1a/1a receptors, mixed effect at mGlu_5a/5b receptors; agonist at group II metabotropic glutamate receptors.

Racemate also available.

Technical Data for (S)-4-Carboxy-3-hydroxyphenylglycine

M. Wt	211.17
Formula	C₉H₉NO₅
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	85148-82-9
PubChem ID	5311455
InChi Key	GXZSAQLJWLCLOX-ZETCQYMHSA-N
Smiles	OC1=C(C(O)=O)C=CC([C@]([H])(N)C(O)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (S)-4-Carboxy-3-hydroxyphenylglycine

References are publications that support the biological activity of the product.

Sekiyama Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 1996 PMID: 8730745
Hayashi Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types. J.Neurosci. 1994 PMID: 8182479
Kingston Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects mGluR1α and mGluR5a subtypes. Neuropharmacology 1995 PMID: 8532170
Birse Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system Neuroscience 1993 PMID: 7680790

(S)-4-Carboxy-3-hydroxyphenylglycine

Tocris Bioscience, part of Bio-Techne | Catalog # 0320

Key Product Details

Biological Activity for (S)-4-Carboxy-3-hydroxyphenylglycine

Technical Data for (S)-4-Carboxy-3-hydroxyphenylglycine

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (S)-4-Carboxy-3-hydroxyphenylglycine

Product Documents for (S)-4-Carboxy-3-hydroxyphenylglycine

COA

Certificate of Analysis

SDS

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