S 2101
Tocris Bioscience, part of Bio-Techne | Catalog # 5714
LSD1 inhibitor
Product Description
S 2101 is a LSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM). Exhibits selectivity for LSD1 over MAO-B and MAO-A (Ki values are 17 and 110 μM, respectively).Product Specifications
Molecular Weight
311.75
Formula
C16H15F2NO.HCl
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
(1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
CAS Number
1239262-36-2
PubChem ID
121513887
InChI Key
CTSUZAFTJVLOIX-SBKWZQTDSA-N
SMILES
FC1=CC([C@@H]2C[C@H]2N)=C(OCC3=CC=CC=C3)C(F)=C1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.59 | 50 | |
| DMSO | 31.18 | 100 |
Preparing Stock Solutions
for S 2101
The following data is based on the product molecular weight 311.75
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.21 mL | 16.04 mL | 32.08 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.42 mL |
| 10 mM | 0.32 mL | 1.60 mL | 3.21 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.64 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mimasu Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1. Biochemistry 2010 PMID: 20568732
Product Specific Notices for S 2101
For research use only
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