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Ruthenium Red

Tocris Bioscience a Bio-Techne Brand

Cav2.x Channel Blockers Small Molecule
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Key Product Details

Description: Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels
Chemical Name: Ammoniated ruthenium oxychloride
Molecular Weight: 786.35

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Citations for Ruthenium Red (18)

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  • Ruthenium red blocks RyR2-mediated oscillations in HEK293 cells.
    Name: Niroj Shrestha
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK293
    HEK293 cells, stably expressing RyR2 receptors, were loaded with intracellular Ca2+ sensitive dye, Fura2AM and excited alternately at 340 and 380 nm and fluorescence at 510 nm was expressed as 340/380 ratio. These cells elicit store-overload induced Ca2+ release (cytosolic oscillations) via RyR2 in presence of 2 mM extracellular Ca2+. 10 μM ruthenium red blocks RyR2 and subsequent Ca2+ release and oscillations in these cells.
    Ruthenium Red Serum 1439

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Product Documents for Ruthenium Red

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