RS 246204
Tocris Bioscience, part of Bio-Techne | Catalog # 8853
R-Spondin-1 substitute used to initiate small intestinal organoids
Key Product Details
Description
R-Spondin-1 substitute used to initiate small intestinal organoids
Product Description
RS 246204 is a R-Spondin-1 substitute. Able to initiate formation and growth of mouse intestinal organoids in media without R-Spondin-1 protein. In vivo, RS 24620 has regenerative effect in damaged intestinal epithelium mouse model.Product Specifications
Molecular Weight
339.37
Formula
C16H13N5O2S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
3,7-Dihydro-3,7-dimethyl-8-(2-quinolinylthio)-1H-purine-2,6-dione
CAS Number
878451-87-7
PubChem ID
6485821
InChI Key
UHUHSGFUUWVRBO-UHFFFAOYSA-N
SMILES
O=C1NC(N(C)C2=C1N(C)C(SC3=CC=C4C=CC=CC4=N3)=N2)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 1.7 | 5 |
Preparing Stock Solutions
for RS 246204
The following data is based on the product molecular weight 339.37
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.05 mM | 58.93 mL | 294.66 mL | 589.33 mL |
| 0.25 mM | 11.79 mL | 58.93 mL | 117.87 mL |
| 0.5 mM | 5.89 mL | 29.47 mL | 58.93 mL |
| 2.5 mM | 1.18 mL | 5.89 mL | 11.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nam Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture. Oncotarget 2017 PMID: 29464078
Product Specific Notices for RS 246204
For research use only
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