Key Product Details
Description: | Inhibits complex I of the mitochondrial electron transport chain |
Chemical Name: | (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one |
Purity: | ≥95% (HPLC) |
Molecular Weight: | 394.42 |
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Citations for Rotenone (7)
Citations are publications that use Bio-Techne products. Selected citations for Rotenone include:
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Battefeld et al.
(2019)
High-Frequency Microdomain Ca2+ Transients and Waves during Early Myelin Internode Remodeling.
Cell Rep.
26:182
PMID: 30605675 -
Moloney et al.
(2017)
Subcellular localization of the FLT3-ITD oncogene plays a significant role in the production of NOX- and p22(phox)-derived reactive oxygen species in acute myeloid leukemia.
Leuk Res.
52:34
PMID: 27870947 -
Martin et al.
(2017)
A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.
Cell Rep.
20:427
PMID: 28700943 -
Agarwal et al.
(2017)
Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.
Neuron.
93:587
PMID: 28132831 -
Banh et al.
(2016)
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.
Nat Cell Biol.
18:803
PMID: 27323329 -
Beyer et al.
(2014)
An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles.
Am J Physiol Heart Circ Physiol.
307:H1587
PMID: 25260615 -
Juliana et al.
(2012)
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.
Leukemia.
287:36617
PMID: 22948162
There are no citations that match your criteria.
Customer Reviews for Rotenone (2)
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Species: RatAssay Type: In VitroCell Line/Tissue: motor neuronsEffect of rotenone (10 micromolar) on AMPA induced ROS formation in motor neurons.
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Species: HumanAssay Type: Ex VivoCell Line/Tissue: PlateletsI use it to inhibit mitochondrial electron transport chain in platelets. It helps to understand the role of mitochondria in thrombosis.Nice delivery time and all works well!
There are no reviews that match your criteria.