Rimcazole dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1497

σ2 antagonist. Also DAT inhibitor
Catalog #
Availability
Size / Price
Qty
1497/10
1497/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

σ2 antagonist. Also DAT inhibitor

Alternative Names

BW 234U

View all Sigma2 Receptor Antagonists »

Product Description

Rimcazole dihydrochloride is an antagonist at σ receptors (IC50 values are 1480 and 386 nM at σ1 and σ2 receptors respectively). Also binds to the dopamine transporter (IC50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo.

Product Specifications

Molecular Weight

394.39

Formula

C21H27N3.2HCl

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]-9H-carbazole dihydrochloride

CAS Number

75859-03-9

PubChem ID

53388

InChI Key

ZWHRZGHGYMUSRM-VWDRLOGHSA-N

SMILES

C[C@H](N[C@H](C)C4)CN4CCCN1C3=C(C=CC=C3)C2=C1C=CC=C2.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.94 10

Preparing Stock Solutions for Rimcazole dihydrochloride

The following data is based on the product molecular weight 394.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.36 mL 126.78 mL 253.56 mL
0.5 mM 5.07 mL 25.36 mL 50.71 mL
1 mM 2.54 mL 12.68 mL 25.36 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for Rimcazole dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rimcazole dihydrochloride

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.