RHPS 4 methosulfate

Tocris Bioscience, part of Bio-Techne | Catalog # 5311

Telomerase inhibitor
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Key Product Details

Description

Telomerase inhibitor

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Product Description

RHPS 4 methosulfate is a telomerase inhibitor. Inhibits growth of medulloblastoma and glioblastoma cells in vitro. Induces telomere injury and apoptosis, and reduces growth in CG5 breast cancer cell xenografts in mice. Sensitizes radiation resistant glioblastoma cell lines to radiation.

Product Specifications

Molecular Weight

458.48

Formula

C22H17F2N2.CH3O4S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

3,11-Difluoro-6,8,13-trimethylquino[4,3,2-kl]acridinium methylsulfate

CAS Number

390362-78-4

PubChem ID

9804187

InChI Key

VRWGYMXWYZBBGF-UHFFFAOYSA-M

SMILES

C[N+]4=C2C3=C(C=C(C)C=C3C5=C4C=CC(F)=C5)N(C)C1=CC=C(F)C=C12.COS(=O)([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 4.58 10 with gentle warming
DMSO 9.17 20

Preparing Stock Solutions for RHPS 4 methosulfate

The following data is based on the product molecular weight 458.48

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 10.91 mL 54.53 mL 109.06 mL
1 mM 2.18 mL 10.91 mL 21.81 mL
2 mM 1.09 mL 5.45 mL 10.91 mL
10 mM 0.22 mL 1.09 mL 2.18 mL

Calculators

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Reconstitution Calculator

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Product Documents for RHPS 4 methosulfate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RHPS 4 methosulfate

For research use only

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