RCGD 423
Tocris Bioscience, part of Bio-Techne | Catalog # 7066
gp130 modulator; activates JAK/STAT signaling
Discontinued Product
7066 has been discontinued.
View all gp130 products.
Product Description
RCGD 423 is a gp130 modulator. Binds gp130, promotes Myc expression, increases lactate production and activates downstream JAK/STAT signaling pathways in hair follicle stem cells. Also increases articular chondrocyte activation and facilitates joint repair by regulating cartilage growth and differentiation.Product Specifications
Molecular Weight
331.23
Formula
C15H11BrN2S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-(4-Bromophenyl)-4-phenyl-2-thiazolamine
CAS Number
108237-91-8
PubChem ID
4456143
InChI Key
OUFYYVAASPLOAA-UHFFFAOYSA-N
SMILES
BrC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.12 | 100 | |
| Ethanol | 33.12 | 100 |
Preparing Stock Solutions
for RCGD 423
The following data is based on the product molecular weight 331.23
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.02 mL | 15.10 mL | 30.19 mL |
| 5 mM | 0.60 mL | 3.02 mL | 6.04 mL |
| 10 mM | 0.30 mL | 1.51 mL | 3.02 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Alam A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS.Chem.Neurosci. 2018 PMID: 29161500
- Flores Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat.Cell Biol. 2017 PMID: 28812580
Product Specific Notices for RCGD 423
For research use only
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