(R)-CPP

Tocris Bioscience, part of Bio-Techne | Catalog # 0247

Potent NMDA antagonist; more active enantiomer of (RS)-CPP
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Key Product Details

Description

Potent NMDA antagonist; more active enantiomer of (RS)-CPP

View all NMDA Receptor Antagonists »

Product Description

(R)-CPP is a highly potent NMDA antagonist; more active isomer. Shows some selectivity for GluN2A (formally NR2A) containing receptors (Ki values are 0.041, 0.27, 0.63 and 1.99 μM for inhibition of GluN2A-, GluN2B-, GluN2C- and GluN2D-containing recombinant NMDA receptors respectively).

Racemate also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Product Specifications

Molecular Weight

252.21

Formula

C8H17N2O5P

Storage

Desiccate at RT

Chemical Name

3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid

CAS Number

126453-07-4

PubChem ID

6603754

InChI Key

CUVGUPIVTLGRGI-SSDOTTSWSA-N

SMILES

[H][C@@]1([C@](O)=O)NCCN(CCCP(O)(O)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 25.22 100

Preparing Stock Solutions for (R)-CPP

The following data is based on the product molecular weight 252.21

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.96 mL 19.82 mL 39.65 mL
5 mM 0.79 mL 3.96 mL 7.93 mL
10 mM 0.40 mL 1.98 mL 3.96 mL
50 mM 0.08 mL 0.40 mL 0.79 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for (R)-CPP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (R)-CPP

For research use only

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