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Pyrrolidinedithiocarbamate ammonium

NFkB/IkB Inhibitors Small Molecule

Key Product Details

Description: Inhibits NF-κB, prevents increase in NOS mRNA
Alternative Names: PDTC

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Citations (8)

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  • PDTC inhibits HOCl-LDL-induced CaMKII oxidation
    Name: Chintan Koyani | 22nd Oct 2018
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Cardiomyocytes
    HL-1 cardiomyocytes were pre-treated with Pyrrolidinedithiocarbamate (PDTC, 1 mM), Tempol (1 mM) or N-Acetylcysteine (NAC, 1 mM) for 30 min and stimulated with HOCl-LDL (200 µg/ml) for 2 h to follow CaMKII oxidation using Western blot.
    PDTC inhibits HOCl-LDL-induced CaMKII oxidation Serum 0727

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