Progesterone

Name: Progesterone
Brand: Tocris Bioscience
SKU: 2835

Tocris Bioscience, part of Bio-Techne | Catalog # 2835

Citations (61)

COA / SDS

Endogenous progesterone receptor agonist

Key Product Details

Description:	Endogenous progesterone receptor agonist
Chemical Name:	Pregn-4-ene-3,20-dione
Purity:	≥98% (HPLC)
Molecular Weight:	314.46

View Full Technical Details for Progesterone

Technical Data
Citations

Biological Activity for Progesterone

Progesterone is an endogenous progesterone receptor (PR) agonist (EC₅₀ = 0.5 nM).

Technical Data for Progesterone

M. Wt	314.46
Formula	C₂₁H₃₀O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	57-83-0
PubChem ID	5994
InChi Key	RJKFOVLPORLFTN-LEKSSAKUSA-N
Smiles	O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](C)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Progesterone

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	31.45	100
	ethanol	31.45	100

Preparing Stock Solutions for Progesterone

The following data is based on the product molecular weight 314.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.18 mL	15.90 mL	31.80 mL
5 mM	0.64 mL	3.18 mL	6.36 mL
10 mM	0.32 mL	1.59 mL	3.18 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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References for Progesterone

References are publications that support the biological activity of the product.

Jerry Roles of estrogen and progesterone in breast cancer prevention. Breast Cancer Res. 2007 PMID: 17381827
Dong Characterization of a new class of selective nonsteroidal progesterone receptor agonist. Steroids 2004 PMID: 15072922

Product Documents for Progesterone

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Progesterone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov