Progesterone
Tocris Bioscience, part of Bio-Techne | Catalog # 2835
Endogenous progesterone receptor agonist
Key Product Details
Description
Endogenous progesterone receptor agonist
Product Description
Progesterone is an endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).Product Specifications
Molecular Weight
314.46
Formula
C21H30O2
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
Pregn-4-ene-3,20-dione
CAS Number
57-83-0
PubChem ID
5994
InChI Key
RJKFOVLPORLFTN-LEKSSAKUSA-N
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](C)=O)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.45 | 100 | |
| Ethanol | 31.45 | 100 |
Preparing Stock Solutions
for Progesterone
The following data is based on the product molecular weight 314.46
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.18 mL | 15.90 mL | 31.80 mL |
| 5 mM | 0.64 mL | 3.18 mL | 6.36 mL |
| 10 mM | 0.32 mL | 1.59 mL | 3.18 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.64 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Jerry Roles of estrogen and progesterone in breast cancer prevention. Breast Cancer Res. 2007 PMID: 17381827
- Dong Characterization of a new class of selective nonsteroidal progesterone receptor agonist. Steroids 2004 PMID: 15072922
Product Specific Notices for Progesterone
For research use only
⚠ WARNING: This product can expose you to chemicals including Progesterone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov
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