PR 39 (porcine)

Name: PR 39 (porcine)
Brand: Tocris Bioscience
SKU: 1947

Tocris Bioscience, part of Bio-Techne | Catalog # 1947

Citations (21)

COA / SDS

IκBα inhibitor

Discontinued Product

1947 has been discontinued. View all NFkB/IkB Inhibitors products.

Key Product Details

Description:	IκBα inhibitor
Molecular Weight:	4719.7

View Full Technical Details for PR 39 (porcine)

Technical Data
Citations

Biological Activity for PR 39 (porcine)

PR 39 (porcine) is an antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.

Technical Data for PR 39 (porcine)

M. Wt	4719.7
Formula	C₂₂₉H₃₄₆N₇₀O₄₀
Single Letter Sequence	RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP (Modifications: Pro-39 = C-terminal amide)
Storage	Desiccate at -20°C
CAS Number	139637-11-9
PubChem ID	52949575
InChi Key	SVJCYLXJXIRSHM-IWDHFESKSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PR 39 (porcine)

References are publications that support the biological activity of the product.

Gao Inhibition of ubiquitin-proteasome pathway-mediated IκBα degradation by a naturally occuring antibacterial peptide. J.Clin.Invest. 2000 PMID: 10930447
Li PR39, a peptide regulator of angiogenesis. Nat.Med. 2000 PMID: 10613823
Gaczynska Proline and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity. Biochemistry 2003 PMID: 12873125

PR 39 (porcine)

Tocris Bioscience, part of Bio-Techne | Catalog # 1947

Key Product Details

Biological Activity for PR 39 (porcine)

Technical Data for PR 39 (porcine)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PR 39 (porcine)

Product Documents for PR 39 (porcine)

COA

Certificate of Analysis

SDS

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