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POM 1

Tocris Bioscience a Bio-Techne Brand

NTPDase Inhibitors Small Molecule
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Key Product Details

Description: Inhibitor of E-NTPDases
Alternative Names: Sodium polyoxotungstate
Chemical Name: Sodium metatungstate
Molecular Weight: 2986.01

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Citations for POM 1 (12)

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  • POM-1 inhibits PBMCs CD39 activity
    Name: Anonymous
    Species: Human
    Assay Type: Ex Vivo
    Cell Line/Tissue: PBMCs
    Human PBMCs were incubated with 10 μM POM-1 for 30 minutes to inhibit CD39 ATPase activity. POM-1 caused a 80% inhibition of PBMCs ATPase activity.
    PBMCs were isolated from healthy subjects and from multiple sclerosis patients and CD39 activity was measured by the Malachite Green Phosphate Assay. Cells were washed in phosphate-free buffer and incubated with ATP (250 μM) for 30 minutes at 37ºC. To selectively assess CD39 ATPase activity, POM-1 (10 μM) was added while cells were incubated with ATP.
    POM 1 Serum 2689

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Product Documents for POM 1

Certificate of Analysis

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