PLP (139-151)
Tocris Bioscience, part of Bio-Techne | Catalog # 2567
Encephalitogenic myelin proteolipid fragment
Key Product Details
Description
Encephalitogenic myelin proteolipid fragment
Alternative Names
Proteolipid protein (139-151)
Product Description
PLP (139-151) is a synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.Product Specifications
Molecular Weight
1521.74
Formula
C72H104N20O17
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
122018-58-0
PubChem ID
16199055
InChI Key
UQIBUOXNUPHALR-UVIWMAFZSA-N
SMILES
[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Sobel Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J.Neuropathol.Exp.Neurol. 1990 PMID: 2273404
- Kuchroo Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology. 1991 PMID: 1716908
- Tuohy Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J.Immunol. 1989 PMID: 2465343
Product Specific Notices for PLP (139-151)
For research use only
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