Piroxicam

Name: Piroxicam
Brand: Tocris Bioscience
SKU: 0960

Bio-Techne includes Tocris Bioscience | Catalog # 0960

COA / SDS

Cyclooxygenase-1 (COX-1) inhibitor

Discontinued Product

0960 has been discontinued. View all Cyclooxygenase Inhibitors products.

Key Product Details

Description:	Cyclooxygenase-1 (COX-1) inhibitor
Chemical Name:	3,4-Dihydro-2-methyl-4-oxo-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Purity:	≥99% (HPLC)
Molecular Weight:	331.35

View Full Technical Details for Piroxicam

Technical Data
Citations

Biological Activity for Piroxicam

Piroxicam is an anti-inflammatory; highly selective inhibitor of COX-1 (ratio of IC₅₀ values for COX-2/COX-1 ~ 600).

Technical Data for Piroxicam

M. Wt	331.35
Formula	C₁₅H₁₃N₃O₄S
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	36322-90-4
PubChem ID	54676228
InChi Key	QYSPLQLAKJAUJT-UHFFFAOYSA-N
Smiles	CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=CC=C2)S1(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Piroxicam

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions for Piroxicam

The following data is based on the product molecular weight 331.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.02 mL	15.09 mL	30.18 mL
5 mM	0.60 mL	3.02 mL	6.04 mL
10 mM	0.30 mL	1.51 mL	3.02 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

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Reconstitution Calculator

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References for Piroxicam

References are publications that support the biological activity of the product.

Mitchell Cyclooxygenase-2. Regulation and relevance in inflammation. Biochem.Pharmacol. 1995 PMID: 7503754