Piroxicam

Name: Piroxicam
Brand: tocris
SKU: 0960

Catalog # 0960

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (612) 379-2956

tel: (800) 343-7475 (free phone)

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	Cyclooxygenase-1 (COX-1) inhibitor
Chemical Name:	3,4-Dihydro-2-methyl-4-oxo-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Purity:	≥99% (HPLC)

View Full Technical Details for Piroxicam

Biological Activity

Anti-inflammatory; highly selective inhibitor of COX-1 (ratio of IC₅₀ values for COX-2/COX-1 ~ 600).

Technical Data

M. Wt	331.35
Formula	C₁₅H₁₃N₃O₄S
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	36322-90-4
PubChem ID	54676228
InChi Key	QYSPLQLAKJAUJT-UHFFFAOYSA-N
Smiles	CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=CC=C2)S1(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions

The following data is based on the product molecular weight 331.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.02 mL	15.09 mL	30.18 mL
5 mM	0.60 mL	3.02 mL	6.04 mL
10 mM	0.30 mL	1.51 mL	3.02 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Mitchell Cyclooxygenase-2. Regulation and relevance in inflammation. Biochem.Pharmacol. 1995 PMID: 7503754
Merck Index