Photo-lenalidomide-acid
Tocris Bioscience, part of Bio-Techne | Catalog # 7328
Functionalized photoswitchable cereblon ligand for Degraders
Discontinued Product
7328 has been discontinued.
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Key Product Details
Description
Functionalized photoswitchable cereblon ligand for Degraders
Product Description
Photo-lenalidomide-acid is a functionalized cereblon ligand containing a dimethoxy azo-benzene photoswitch; for use as a precursor to photoswitchable Degraders (PHOTACs). Photo-lenalidomide-acid is supplied with a carboxylic acid functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for Degrader R&D.Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
482.45
Formula
C23H22N4O8
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(E)-2-(4-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)diazenyl)-2,6-dimethoxyphenoxy)acetic acid
CAS Number
2363154-39-4
InChI Key
CGLOIOJVUYAUAC-OCEACIFDSA-N
SMILES
COC1=CC(/N=N/C2=C3CN(C(C3=CC=C2)=O)C4CCC(NC4=O)=O)=CC(OC)=C1OCC(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
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Background References
References are publications that support the biological activity of the product.
- Reynders PHOTACs enable optical control of protein degradation. Sci.Adv. 2020 PMID: 32128406
Product Specific Notices for Photo-lenalidomide-acid
For research use only
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